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Brain modifications that occur over time as a result of chronic drug use offer a challenge to a drug addict's self-control and interfere with their ability to resist overwhelming desires to use drugs. As a result, substance addiction is a disease that leads to relapses.
Someone who relapses after making an effort to stop taking drugs will begin using them again. A relapse indicates that further therapy or a different therapeutic strategy is necessary.
The vast majority of drugs act by flooding the brain's reward circuit with the chemical messenger dopamine. The dopamine spikes that occur in the reward circuit are what drive the reinforcing of pleasant but dangerous behaviours. As a result, people are prone to repeating similar behaviours.

People who abuse chronically drugs are more likely to have brain changes that compromise their self-control and can't resist the urge to use. Drug addiction is also known as relapse.

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The brain sends large amounts of dopamine to its reward circuit, which is how most medications work. Dopamine surges in the reward circuit keep people engaged in activities that are not only enjoyable but also harmful to their health. These actions are often repeated by people.
The brain becomes more used to the dopamine and the person feels less high after a while. This is called tolerance. In an effort to feel the same dopamine rush, they may take more medication.
There is no single factor that can predict if someone will become dependent on drugs. It is possible for many factors to influence whether or not someone will become addicted. A person is more likely to use drugs if they have more risk factors.

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The brain changes caused by chronic drug abuse lead to impaired self-control and reduced ability to resist acute drug cravings. Drug addiction can also lead to relapse.
Relapse is when you return to using drugs after a period of abstinence. Relapse means that you require additional treatment or another method.

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Tolerance happens when the brain adapts and produces less dopamine than the dose they took at first. They may increase their dopamine intake to get the maximum amount of dopamine.

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At first, you could decide to use a drug because you enjoy the way it makes you feel. But eventually, you can come to regret your decision. You could believe that you have complete control over how much and how frequently you use it. But taking medicines over and over will change the way your brain works. Some of these changes to a person's body can last for a long time. They cause you to lose control and might lead to activities that are detrimental to you.

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The following is important: Drug addiction refers to a chronic condition that involves obsessive drug searching and use.
Brain alterations resulting from drug addiction test an addict's ability to control their behavior and reduce their tolerance for acute drug cravings. This is why drug addiction is a chronic illness.
Relapse is when you return to drug use after a period of abstinence. Relapse indicates that additional or alternate therapy is needed.